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Comorbidity

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This page contains information and summaries of published research that are intended for people with professional training in mental health.  We urge caution since it may be difficult to know how to interpret the information without advanced training in psychology or psychiatry.

We recommend that readers interested in information intended for the general public check other areas of this web site (such as Info for Adults or Info for Children).  They contain similar information, but in a more readable form.  Also, elsewhere we have provided links to other websites that we feel may be helpful.

 

COMORBIDITY

 

The National Comorbidity Study found that 88.3% of men and 79.0% of women with a lifetime diagnosis of PTSD met criteria for at least one other disorder” (Kessler et al., 1995).

bullet U.S. epidemiological findings indicate that 80% of people with lifetime PTSD suffer from lifetime depression, another anxiety disorder, or chemical abuse/dependency (Foa et al., 2000)
It appears that depression usually develops after PTSD.  In one study, 78.4% of participants with comorbid major depression and PTSD reported that the onset of their depression followed that of PTSD (Kessler et al., 1995).
bulletLifetime prevalence rates of alcohol abuse/dependence among men and women with PTSD are about 52% and 28% respectively, and current prevalence rates for drug abuse/dependence are 35% and 27% respectively (Foa et al., 2000)
bulletWork, marital, and family problems are more common (Foa & Rothbaum, 1998).

 

   

Even subthreshold symptoms of PTSD are associated with significant comorbidity:

bulletImpairment, number of comorbid disorders, rates of comorbid major depressive disorder, and current suicidal ideation increased linearly and significantly with each increasing number of subthreshold PTSD symptoms. Individuals with subthreshold PTSD were at greater risk for suicidal ideation even after the authors controlled for the presence of comorbid major depressive disorder” (Marshall et al., 2001).
bullet“rates of impairment, comorbid anxiety disorders, and comorbid major depressive disorder were 31.5%, 68.5%, and 90.7% higher, respectively, among the subjects with four PTSD symptoms than among the subjects with no PTSD symptoms” (Marshall et al., 2001).

   

19% of rape victims make a suicide attempt, 44% consider it

(Foa & Rothbaum, 1998)

   

Trauma survivors report more medical symptoms, use more medical services, have more medical illnesses detected during physical examinations, and display higher mortality (Foa et al., 2000). 

·         Those with PTSD are more likely to have significant health problems such as hypertension, bronchial asthma, peptic ulcer, and GI problems.  They also have increased rates of surgery and doctor visits

·         The number of lymphocytes, number of T cells, NK cell activity, and total amounts of IFN- {gamma} and IL-4 were significantly lower in the 12 men with a past history of PTSD. . .  PTSD leaves a long-lasting immunosuppression and has long-term implications for health” (Kawamura, N., Kim, Y., & Asukai, N., 2001).

   

PTSD also has cognitive effects:

bulletPTSD is also associated with deficits in short term memory, but not WAIS-R scores (Bremner et al., 1993):
“The PTSD patients scored significantly lower than the comparison subjects on the Wechsler Memory Scale logical memory measures for immediate recall (mean = 11.6, SD = 3.3 versus mean = 20.9, SD = 6.6) and delayed recall (mean = 8.0, SD = 3.3 versus mean = 17.8, SD = 6.4).”

See “Biological Findings and Theory” section for other cognitive effects of PTSD  

 

 

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The information posted on this site reflects our understanding of peer-reviewed research and generally accepted principles in psychology.  It is not intended to be used for self-treatment or as a substitute for individualized assessment and treatment by a licensed professional, and should not be construed as professional advice.

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