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PTSD Tx Chart

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This page contains information and summaries of published research that are intended for people with professional training in mental health.  We urge caution since it may be difficult to know how to interpret the information without advanced training in psychology or psychiatry.

We recommend that readers interested in information intended for the general public check other areas of this web site (such as Info for Adults or Info for Children).  They contain similar information, but in a more readable form.  Also, elsewhere we have provided links to other websites that we feel may be helpful.

 

CONTROLLED RESEARCH ON TREATMENT EFFICACY:

 

Conclusion of the International Society for Traumatic Stress Studies

Treatment Guidelines Task Force:

“Comparing the numbers and types of studies supporting each type of treatment EX [Prolonged Exposure] has the most studies and the greatest number of well-controlled studies to support its use.  EX has been tested in 12 studies, all finding positive results for this treatment with PTSD.  These are also generally methodologically controlled studies, eight of which received the AHCPT Level A rating, with many meeting many of the gold standards for clinical outcome studies (Foa & Meadows, 1997); thus the strength of evidence for EX is very conclusive.  In one study, EX was superior to SIT and SIT/PE.  Additionally, EX has been tested in a wider range of trauma populations and more studies than any of the other treatments.  Thus, we strongly recommend the use of some form of EX in the treatment of PTSD unless otherwise indicated.  In conclusion, the evidence is very compelling from many well-controlled trials with a mixed variety of trauma survivors that EX is effective.  In fact, no other treatment modality has such strong evidence for its efficacy. . . EX has received the strongest evidence for PTSD; thus, it should be considered the first line treatment unless reasons exist for ruling it out” (Foa et al., 2000).

 

Psychosocial Treatments for PTSD That Have Been Studied Through Controlled Clinical Trials

(Foa et al., 2000; Foa & Rothbaum, 1998)

Prolonged Exposure (PE - Foa)

 

12 empirical studies, 8 of which were “gold standard.”  Generally, about 75-80% of participants had at least a 70% reduction in symptoms within the 9-12 session protocol.  Low relapse rates, and some indications that participants continue to improve after therapy is over.  Treatment involves relaxation followed by structured, imaginal reexposure and in vivo exposure exercises.  “No other treatment modality has such strong evidence for its efficacy” (ISTSS Treatment Guidelines Task Force).  (9-12 sessions)

Stress Inoculation Training (SIT - Meichenbaum)

4 Studies, 2 of which were very well controlled.  Support and findings similar to, but not as strong as, those for PE, but they take a firm second place.  Treatment has several components, including relaxation, skills training, and exposure.  (9-12 sessions)

Combined PE and SIT

1 well-controlled study.  Findings are that a combination of SIT and PE are as effective, but not more effective that either component alone.

Cognitive Processing Therapy (CPT – Resick)

2-3 studies (although more in the pipeline).  Preliminary findings have shown promise, but more research is needed.  Preliminary evidence suggests that it may be better than PE at reducing cognitions related to guilt (9-12 sessions)

Cognitive Therapy

2 well controlled studies demonstrating efficacy.  Evidence is considered preliminary by many researchers, however.

Systematic Desensitization (SD - Wolpe)

6 studies that were not well controlled.  Outcomes have not given strong support to efficacy.  Generally abandoned in favor of PE since opinion seems to be that the intermittent relaxation element of SD prolongs treatment but does not enhance effectiveness.  (9-12 sessions)

Assertiveness Training

One study, not well controlled.  Not significantly different from comparison treatments.

Biofeedback and Relaxation Training

One study for biofeedback and several for relaxation.  Findings indicate that they are less effective than comparison treatments.

Eye Movement Desensitization and Reprocessing (EMDR)

Proponents have made remarkable claims (e.g., one session cures, etc), but these claims have not been supported by controlled research trials.  Probably more effective than placebo or non-specific therapy, and efficacy may be close to that of PE.  But most studies have not been well designed (e.g., no standardized measures, not “blind,” etc.). Research indicates eye movements are not necessary, leaving a protocol that bears some similarity to exposure-based treatment.

Unfortunately, there are no studies that systematically examine the value of combining psychotherapy with medication or combinations of medications.

 

In one examination of inpatient Tx for Vietnam Vets with PTSD, no positive results were found (Johnson et al., 1996). Psychodynamic approaches, creative therapy, and marital therapy have not been examined using well-controlled research.  Available studies have found that they do not appear to show efficacy in treating PTSD.  Research on psychoanalytic psychotherapy is similar, with one study reporting iatrogenic effects.

 

Writing about the trauma, whether or not one focuses on affect or shares the writing, is associated with reductions in dysphoria and social anxiety (Brown & Heimber, 2001).  Number of words in the self-references in writing had a curvilinear relationship with Sx reduction (moderate number of self references associated with fewer Sx).

   

 

 

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The information posted on this site reflects our understanding of peer-reviewed research and generally accepted principles in psychology.  It is not intended to be used for self-treatment or as a substitute for individualized assessment and treatment by a licensed professional, and should not be construed as professional advice.

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